Paragon® Oxygenators

Paragon® is the only Extracorporeal Membrane Oxygenator to be manufactured in the UK.

The tailor-made, precision manufacturing process allows a greater degree of control over every aspect of its production, enabling quality and attention to detail achieved at all stages.

Every Paragon® is carefully monitored and tested over and above standard clinical requirements – making every effort to safeguard performance, reliability and to instil confidence.

25 checks for every unit

Every Paragon is monitored and tested over and above standard clinical requirements – making every effort to safeguard performance and reliability.

Patient Population

The Paragon range accommodates a diverse and complete patient range – catering for new born neonates all the way up to fully grown large adults.

Coated as Standard

Every unit is coated as standard with our proprietary surface coating: Rheopak – proven to increase biocompatibility through reduced platelet adhesion.

The Paragon range is available in 3 different models to accommodate end user requirements in different situations:

The standard Paragon Oxygenator has a Polypropylene Micro Porous Fibre Gas Exchanger and is available either as a separate stand-alone product, or as an integrated unit when used in conjunction with the Paragon venous & cardiotomy reservoir – making a complete and dependable system. 

The Standard Paragon has an intended use of up to 6 hours.

The Paragon MicroNet is identical to the standard Paragon with the exception of a highly efficient filter membrane incorporated in to the Polypropylene gas exchanger. The MicroNet filter has a composition allowing a 40% open area, helping to maintain low blood side pressures as it filters out micro aggregate down to 40µ.

This popular model can contribute to reduced circuit priming volumes and costs as some end users choose to remove their traditional arterial filter and rely on the highly efficient internal filter of the oxygenator.  The Paragon MicroNet has an intended use of up to 24 hours.

The Paragon PMP is a stand-alone unit that is specifically designed for long-term applications such as ECMO/ECLS.  Possessing all the benefits and features as the standard Paragon, but with the exception of a Polymethylpentene Plasma Tight Fibre Gas Exchanger, an essential requirement to allow extended use.

The Paragon PMP has an intended use of up to 24 hours.

The Paragon Oxygenator is manufactured in 5 different sizes to accommodate a range of patient sizes.  Each size of Paragon is available as a stand-alone item or an integrated “open system” unit when coupled together with a Venous & Cardiotomy Reservoir.

Click here to view details of the compatible Paragon Reservoir range.

The largest and most powerful models in the Paragon® range - accommodating a diverse adult population for ECMO.

Paragon Adult Maxi.

The largest and most powerful model in the Paragon® range, designed to accommodate adult patients.

SPECIFICATIONS
Blood Flow Range 1 – 8lpm
Static Priming Volume 303ml*
Heat Exchanger Surface Area 0.4m²
Gas Exchanger Surface Area 2.44m²
40µ Integrated Filter Surface Area 230cm²
Blood Inlet/Outlet 3/8″ Barbed
Gas Inlet 1/4″
Water Inlet/Outlet 3/8″ Hansen
The largest and most powerful models in the Paragon® range - accommodating a diverse adult population for ECMO.

Paragon Adult Midi.

The Adult Midi is the original and cornerstone of the Paragon range – engineered to cover a diverse adult population for both standard bypass and ECMO.

SPECIFICATIONS
Blood Flow Range 1 – 7lpm
Static Priming Volume 274ml*
Heat Exchanger Surface Area 0.4m²
Gas Exchanger Surface Area 1.95m²
40µ Integrated Filter Surface Area 230cm²
Blood Inlet/Outlet 3/8″ Barbed
Gas Inlet 1/4″
Water Inlet/Outlet 3/8″ Hansen
The largest and most powerful models in the Paragon® range - accommodating a diverse adult population for ECMO.

Paragon Paediatric.

The Paragon Paediatric adopts the same successful design and features as its larger family members – with an optimised balance of volume vs performance.

SPECIFICATIONS
Blood Flow Range 1 – 4lpm
Static Priming Volume 175ml*
Heat Exchanger Surface Area 0.2m²
Gas Exchanger Surface Area 1.23m²
40µ Integrated Filter Surface Area 190cm²
Blood Inlet/Outlet 3/8″ Barbed
Gas Inlet 1/4″
Water Inlet/Outlet 3/8″ Hansen
The latest addition to the Paragon® range - optimised to deliver outstanding performance and reliability in ECMO situations.

Paragon Infant.

Optimised to deliver outstanding performance and reliability for smaller patients in ECMO situations.

SPECIFICATIONS
Blood Flow Range 0.5 – 3lpm
Static Priming Volume 150ml*
Heat Exchanger Surface Area 0.2m²
Gas Exchanger Surface Area 0.88m²
40µ Integrated Filter Surface Area 175cm²
Blood Inlet/Outlet 1/4″ Barbed
Gas Inlet 1/4″
Water Inlet/Outlet 3/8″ Hansen
The smallest model in the Paragon® range - catering for the tiniest and most vulnerable patients.

Paragon Neonatal.

The smallest model in the Paragon® range – catering for the tiniest and most vulnerable patients.

SPECIFICATIONS
Blood Flow Range 0.1 – 1.4lpm
Static Priming Volume 63ml*
Heat Exchanger Surface Area 0.07m²
Gas Exchanger Surface Area 0.45m²
Blood Inlet/Outlet 3/16″ Barbed
Gas Inlet 1/4″
Water Inlet/Outlet 3/8″ Hansen

Features and Benefits of Paragon Oxygenators

Paragon Oxygenators are available as seperate units or included in a fully pre-connected tubing pack.

Each unit offers an optimised balance of low priming volume, high o2 transfer and CO2 removal capabilities.

The Paragon employs double safety seals of silicone o’rings and UV adhesive to create a safe and secure closure.

All Paragon Oxygenators must pass 25 separate checks in production before it is made available for clinical use.

Heat exchanger bundle is made from robust Polyester fibres – highly resistant to Hydrogen peroxide cleaning agent.

Increased visibility during setup and use is achieved through separate heat exchanger and gas exchanger bundles.
A batch Lot number and unique Serial number is given to each device to ensure complete traceability.

Custom made holders are available to securely hold each device during setup and throughout use.

*Oxygenator priming volume calculated by establishing weight difference between fully primed and dry device.  Average taken over a number of devices.  Quoted Figures open to +/- 1.5% deviation

(Performance data based on in vitro data; may not be indicative of clinical results. Testing performance is under BS EN ISO 7199, 2017 standard conditions).